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Study Elucidates Role of "G900" Gene Enhancers in Asthma-Associated Inflammation


Type-2 helper T (Th2) cells play intricate roles in the inflammatory response underlying asthma. Elevated levels of the protein GATA3 stimulate the maturation of these cells. Consequently, gene regions known as enhancers, which enhance the expression of the GATA3 gene, have been implicated in asthma-associated inflammation. A study has revealed that the enhancer region G900 may be pivotal in the inflammatory response mediated by Th2 cells, offering clues for new therapeutic strategies.


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