Unraveling the Mystery of Atherosclerosis in Patients with Werner Syndrome
2024.06.11
Patients with Werner syndrome (WS), a rare genetic disease characterized by premature aging, tend to develop atherosclerosis earlier in life. However, the underlying mechanisms are unclear. Now, researchers have developed an innovative co-culturing technique by which the immune cells and vascular cells derived from induced pluripotent stem cells (iPSC) from patients with WS are grown together to analyze their interactions. Understanding the mechanisms underlying WS-associated atherosclerosis can augment the development of potential treatments. 